Wird geladen...

Molecular Imaging of Metabolic Reprograming in Mutant IDH Cells

Mutations in the metabolic enzyme isocitrate dehydrogenase (IDH) have recently been identified as drivers in the development of several tumor types. Most notably, cytosolic IDH1 is mutated in 70–90% of low-grade gliomas and upgraded glioblastomas, and mitochondrial IDH2 is mutated in ~20% of acute m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Viswanath, Pavithra, Chaumeil, Myriam M., Ronen, Sabrina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789800/
https://ncbi.nlm.nih.gov/pubmed/27014635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00060
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!