Structural Characterization and Physicochemical Stability Profile of a Double Mutant Heat Labile Toxin Protein Based Adjuvant

A novel protein adjuvant double-mutant Escherichia coli heat-labile toxin, LT (R192G/L211A) or dmLT, is in preclinical and early clinical development with various vaccine candidates. Structural characterization and formulation development of dmLT will play a key role in its successful process develo...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Pharm Sci
Autori principali: Toprani, Vishal M., Hickey, John M., Sahni, Neha, Toth, Ronald T., Robertson, George A., Middaugh, C. Russell, Joshi, Sangeeta B., Volkin, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690273/
https://ncbi.nlm.nih.gov/pubmed/28780391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.07.019
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi