Preformulation studies with the Escherichia coli double mutant heat-labile toxin adjuvant for use in an oral vaccine

Double mutant heat-labile toxin (dmLT) is a promising adjuvant for oral vaccine administration. The aims of our study were to develop sensitive methods to detect low concentrations of dmLT and to use the assays in preformulation studies to determine whether dmLT remains stable under conditions encou...

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Veröffentlicht in:J Immunol Methods
Hauptverfasser: White, Jessica A., Haghighi, Candace, Brunner, Johanna, Estrada, Marcus, Lal, Manjari, Chen, Dexiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703769/
https://ncbi.nlm.nih.gov/pubmed/28939395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2017.09.003
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