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Preformulation studies with the Escherichia coli double mutant heat-labile toxin adjuvant for use in an oral vaccine

Double mutant heat-labile toxin (dmLT) is a promising adjuvant for oral vaccine administration. The aims of our study were to develop sensitive methods to detect low concentrations of dmLT and to use the assays in preformulation studies to determine whether dmLT remains stable under conditions encou...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: White, Jessica A., Haghighi, Candace, Brunner, Johanna, Estrada, Marcus, Lal, Manjari, Chen, Dexiang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703769/
https://ncbi.nlm.nih.gov/pubmed/28939395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2017.09.003
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