Activation of autophagy ameliorates cardiomyopathy in Mybpc3-targeted knock-in mice

BACKGROUND: Alterations in autophagy have been reported in hypertrophic cardiomyopathy (HCM) caused by Danon disease, Vici syndrome or LEOPARD syndrome, but not in HCM caused by mutations in genes encoding sarcomeric proteins, which account for most of HCM cases. MYBPC3, encoding cardiac myosin-bind...

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Bibliografiset tiedot
Julkaisussa:Circ Heart Fail
Päätekijät: Singh, Sonia R., Zech, Antonia T.L., Geertz, Birgit, Reischmann-Düsener, Silke, Osinska, Hanna, Prondzynski, Maksymilian, Krämer, Elisabeth, Meng, Qinghang, Redwood, Charles, van der Velden, Jolanda, Robbins, Jeffrey, Schlossarek, Saskia, Carrier, Lucie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679453/
https://ncbi.nlm.nih.gov/pubmed/29021349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004140
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