Increased myofilament Ca(2+) sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice

Hypertrophic cardiomyopathy (HCM) is frequently caused by mutations in MYBPC3 encoding cardiac myosin-binding protein C (cMyBP-C). The mechanisms leading from gene mutations to the HCM phenotype remain incompletely understood, partially because current mouse models of HCM do not faithfully reflect t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fraysse, Bodvaël, Weinberger, Florian, Bardswell, Sonya C., Cuello, Friederike, Vignier, Nicolas, Geertz, Birgit, Starbatty, Jutta, Krämer, Elisabeth, Coirault, Catherine, Eschenhagen, Thomas, Kentish, Jonathan C., Avkiran, Metin, Carrier, Lucie
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370652/
https://ncbi.nlm.nih.gov/pubmed/22465693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.03.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados