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Diltiazem prevents stress‐induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3‐knock‐in mice

KEY POINTS: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac illness and can lead to diastolic dysfunction, sudden cardiac death and heart failure. Treatment of HCM patients is empirical and current pharmacological treatments are unable to stop disease progression or reverse hy...

詳細記述

保存先:
書誌詳細
出版年:J Physiol
主要な著者: Flenner, Frederik, Geertz, Birgit, Reischmann‐Düsener, Silke, Weinberger, Florian, Eschenhagen, Thomas, Carrier, Lucie, Friedrich, Felix W.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471503/
https://ncbi.nlm.nih.gov/pubmed/28090637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273769
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