A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway

The ubiquitin-proteasome system (UPS) and the autophagy-lysosomal pathway (ALP) are the main proteolytic systems involved in cellular homeostasis. Since cardiomyocytes, as terminally differentiated cells, lack the ability to share damaged proteins with their daughter cells, they are especially relia...

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Udgivet i:Front Physiol
Main Authors: Wenzel, Kristin, Krämer, Elisabeth, Geertz, Birgit, Carrier, Lucie, Felix, Stephan B., Könemann, Stephanie, Schlossarek, Saskia
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121148/
https://ncbi.nlm.nih.gov/pubmed/33995116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.614878
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