A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway

The ubiquitin-proteasome system (UPS) and the autophagy-lysosomal pathway (ALP) are the main proteolytic systems involved in cellular homeostasis. Since cardiomyocytes, as terminally differentiated cells, lack the ability to share damaged proteins with their daughter cells, they are especially relia...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Wenzel, Kristin, Krämer, Elisabeth, Geertz, Birgit, Carrier, Lucie, Felix, Stephan B., Könemann, Stephanie, Schlossarek, Saskia
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121148/
https://ncbi.nlm.nih.gov/pubmed/33995116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.614878
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