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Using Covalent Labeling and Mass Spectrometry to Study Protein Binding Sites of Amyloid Inhibiting Molecules

Amyloid aggregates are associated with several debilitating diseases, and there are numerous efforts to develop small molecule treatments against these diseases. One challenge associated with these efforts is determining protein binding site information for potential therapeutics because amyloid‐for...

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Bibliografiske detaljer
Udgivet i:Anal Chem
Main Authors: Liu, Tianying, Marcinko, Tyler M., Kiefer, Patrick A., Vachet, Richard W.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677544/
https://ncbi.nlm.nih.gov/pubmed/29028328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b02915
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