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Structure of the Pre-amyloid Dimer of β-2-microglobulin from Covalent Labeling and Mass Spectrometry

β-2-microglobulin (β2m) self-associates into fibrillar amyloid deposits in the musculoskeletal system of patients undergoing hemodialysis treatment. Previous studies have shown that stoichiometric amounts of Cu(II) at near physiological conditions can cause β2m to organize into native-like dimers pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mendoza, Vanessa Leah, Antwi, Kwasi, Barón-Rodríguez, Mario A., Blanco, Cristian, Vachet, Richard W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848472/
https://ncbi.nlm.nih.gov/pubmed/20088607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901748h
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