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Copper Binding to β-2-Microglobulin and its Pre-Amyloid Oligomers
β-2-microglobulin (β2m) deposits as amyloid fibrils in the musculoskeletal system of patients undergoing long-term dialysis treatment as a result of kidney failure. Previous work has shown that Cu(II) binding causes β2m to organize into native-like dimers and tetramers that precede amyloid formation...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766818/ https://ncbi.nlm.nih.gov/pubmed/19754160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901172y |
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