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Epigallocatechin-3-gallate Inhibits Cu(II)-induced β-2-microglobulin Amyloid Formation by Binding to the Edge of its β-sheets

Epigallocatechin-3-gallate (EGCG) is a catechin found in green tea that can inhibit the amyloid formation of a wide variety of proteins. EGCG’s ability to prevent or re-direct the amyloid formation of so many proteins may reflect a common mechanism of action, and thus greater molecular-level insight...

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Publicado en:Biochemistry
Main Authors: Marcinko, Tyler M., Drews, Thomas, Liu, Tianying, Vachet, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080597/
https://ncbi.nlm.nih.gov/pubmed/32100530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00043
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