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Unique Effect of Cu(II) in the Metal-Induced Amyloid Formation of β-2-Microglobulin
[Image: see text] β-2-Microglobulin (β2m) forms amyloid fibrils in the joints of patients undergoing hemodialysis treatment as a result of kidney failure. In the presence of stoichiometric amounts of Cu(II), β2m self-associates into discrete oligomeric species, including dimers, tetramers, and hexam...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985682/ https://ncbi.nlm.nih.gov/pubmed/24450572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4016583 |
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