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Cu(II) organizes β-2-microglobulin oligomers but is released upon amyloid formation
β-2-Microglobulin (β2m) is deposited as amyloid fibrils in the bones and joints of patients undergoing long-term dialysis treatment as a result of kidney failure. Previous work has shown that biologically relevant amounts of Cu(II) can cause β2m to be converted to amyloid fibrils under physiological...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271169/ https://ncbi.nlm.nih.gov/pubmed/18305198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073249008 |
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