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Using Covalent Labeling and Mass Spectrometry to Study Protein Binding Sites of Amyloid Inhibiting Molecules

Amyloid aggregates are associated with several debilitating diseases, and there are numerous efforts to develop small molecule treatments against these diseases. One challenge associated with these efforts is determining protein binding site information for potential therapeutics because amyloid‐for...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Liu, Tianying, Marcinko, Tyler M., Kiefer, Patrick A., Vachet, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677544/
https://ncbi.nlm.nih.gov/pubmed/29028328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b02915
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