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Synergistic Structural Information from Covalent Labeling and Hydrogen-Deuterium Exchange Mass Spectrometry for Protein-Ligand Interactions
Hydrogen deuterium exchange (HDX) mass spectrometry (MS) and covalent labeling (CL) MS are typically considered to be complementary methods for protein structural analysis because one probes the protein backbone while the other probes side chains. For protein-ligand interactions, we demonstrate in t...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891134/ https://ncbi.nlm.nih.gov/pubmed/31664819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b04257 |
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