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Covalent Labeling-Mass Spectrometry with Non-Specific Reagents for Studying Protein Structure and Interactions

Using mass spectrometry (MS) to obtain information about a higher order structure of protein requires that a protein’s structural properties are encoded into the mass of that protein. Covalent labeling (CL) with reagents that can irreversibly modify solvent accessible amino acid side chains is an ef...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Limpikirati, Patanachai, Liu, Tianying, Vachet, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051898/
https://ncbi.nlm.nih.gov/pubmed/29630925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.04.002
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