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Covalent Labeling-Mass Spectrometry with Non-Specific Reagents for Studying Protein Structure and Interactions
Using mass spectrometry (MS) to obtain information about a higher order structure of protein requires that a protein’s structural properties are encoded into the mass of that protein. Covalent labeling (CL) with reagents that can irreversibly modify solvent accessible amino acid side chains is an ef...
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| Pubblicato in: | Methods |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6051898/ https://ncbi.nlm.nih.gov/pubmed/29630925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.04.002 |
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