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Covalent Labeling with Isotopically Encoded Reagents for Faster Structural Analysis of Proteins by Mass Spectrometry
Covalent labeling and mass spectrometry (MS) are increasingly used to obtain higher order structure of proteins and protein complexes. Because most covalent labels are relatively large, steps must be taken to ensure the structural integrity of the modified protein during the labeling reactions so th...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3819941/ https://ncbi.nlm.nih.gov/pubmed/24010814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac401978w |
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