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Structure of the Pre-amyloid Dimer of β-2-microglobulin from Covalent Labeling and Mass Spectrometry
β-2-microglobulin (β2m) self-associates into fibrillar amyloid deposits in the musculoskeletal system of patients undergoing hemodialysis treatment. Previous studies have shown that stoichiometric amounts of Cu(II) at near physiological conditions can cause β2m to organize into native-like dimers pr...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848472/ https://ncbi.nlm.nih.gov/pubmed/20088607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901748h |
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