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Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor

Wilms tumor (WT) is the most common renal malignancy in children and the fourth most common pediatric solid malignancy in the US. Although the mechanisms underlying the WT biology are complex, these tumors most often demonstrate activation of the canonical Wnt/β-catenin pathway. We and others have s...

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Detalhes bibliográficos
Publicado no:Oncol Res
Main Authors: Polosukhina, Dina, Love, Harold D., Moses, Harold L., Lee, Ethan, Zent, Roy, Clark, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670010/
https://ncbi.nlm.nih.gov/pubmed/28695795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504017X14992942781895
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