Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors

Wilms tumor (WT) is the most common renal neoplasm of childhood and affects 1 in 10 000 children aged less than 15 years. These embryonal tumors are thought to arise from primitive nephrogenic rests that derive from the metanephric mesenchyme during kidney development and are characterized partly by...

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Publicado en:Mol Oncol
Autores principales: Polosukhina, Dina, Love, Harold D., Correa, Hernan, Su, Zengliu, Dahlman, Kimberly B., Pao, William, Moses, Harold L., Arteaga, Carlos L., Lovvorn, Harold N., Zent, Roy, Clark, Peter E.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378659/
https://ncbi.nlm.nih.gov/pubmed/28188683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12044
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