Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors

Wilms tumor (WT) is the most common renal neoplasm of childhood and affects 1 in 10 000 children aged less than 15 years. These embryonal tumors are thought to arise from primitive nephrogenic rests that derive from the metanephric mesenchyme during kidney development and are characterized partly by...

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Vydáno v:Mol Oncol
Hlavní autoři: Polosukhina, Dina, Love, Harold D., Correa, Hernan, Su, Zengliu, Dahlman, Kimberly B., Pao, William, Moses, Harold L., Arteaga, Carlos L., Lovvorn, Harold N., Zent, Roy, Clark, Peter E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378659/
https://ncbi.nlm.nih.gov/pubmed/28188683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12044
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