Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors

Wilms tumor (WT) is the most common renal neoplasm of childhood and affects 1 in 10 000 children aged less than 15 years. These embryonal tumors are thought to arise from primitive nephrogenic rests that derive from the metanephric mesenchyme during kidney development and are characterized partly by...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Polosukhina, Dina, Love, Harold D., Correa, Hernan, Su, Zengliu, Dahlman, Kimberly B., Pao, William, Moses, Harold L., Arteaga, Carlos L., Lovvorn, Harold N., Zent, Roy, Clark, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378659/
https://ncbi.nlm.nih.gov/pubmed/28188683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12044
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