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TRAIL and IFNα act synergistically to induce renal cell carcinoma apoptosis

INTRODUCTION: Despite modern targeted therapy, metastatic renal cell carcinoma (RCC) remains a deadly disease. Interferon alpha (IFNα) is currently used to treat this condition, mainly in combination with the targeted anti-VEGF antibody, bevacizumab. Apo2 ligand/Tumor necrosis factor related apoptos...

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Detalhes bibliográficos
Main Authors: Clark, Peter E., Polosukhina, Dina A., Gyabaah, Kenneth, Moses, Harold L., Thorburn, Andrew, Zent, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963111/
https://ncbi.nlm.nih.gov/pubmed/20663526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2010.04.064
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