IFN-γ and TNF-α Act Synergistically to Upregulate Tissue Factor in Alveolar Epithelial Cells

Fibrin deposition mediated through activation of tissue factor (TF) in the airspace is central to the pathogenesis of acute lung injury. Defining the mechanisms of TF regulation in the lung is critical to understanding pulmonary fibrin formation. Tumor necrosis factor-α (TNF-α) upregulates TF in the...

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Detaylı Bibliyografya
Asıl Yazarlar: Bastarache, Julie A., Sebag, Sara C., Grove, Brandon S., Ware, Lorraine B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652424/
https://ncbi.nlm.nih.gov/pubmed/21913843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902148.2011.605512
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