IFN-γ and TNF-α Act Synergistically to Upregulate Tissue Factor in Alveolar Epithelial Cells

Fibrin deposition mediated through activation of tissue factor (TF) in the airspace is central to the pathogenesis of acute lung injury. Defining the mechanisms of TF regulation in the lung is critical to understanding pulmonary fibrin formation. Tumor necrosis factor-α (TNF-α) upregulates TF in the...

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Bibliographic Details
Main Authors: Bastarache, Julie A., Sebag, Sara C., Grove, Brandon S., Ware, Lorraine B.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652424/
https://ncbi.nlm.nih.gov/pubmed/21913843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902148.2011.605512
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