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IFN-γ and TNF-α Act Synergistically to Upregulate Tissue Factor in Alveolar Epithelial Cells
Fibrin deposition mediated through activation of tissue factor (TF) in the airspace is central to the pathogenesis of acute lung injury. Defining the mechanisms of TF regulation in the lung is critical to understanding pulmonary fibrin formation. Tumor necrosis factor-α (TNF-α) upregulates TF in the...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652424/ https://ncbi.nlm.nih.gov/pubmed/21913843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902148.2011.605512 |
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