IFN-γ-induced TNFR2 Upregulation is Required for TNF-dependent Intestinal Epithelial Barrier Dysfunction

BACKGROUND & AIMS: Tumor necrosis factor (TNF) plays critical roles in intestinal disease. In intestinal epithelia, TNF causes tight junction disruption and epithelial barrier loss by upregulating myosin light chain kinase (MLCK) activity and expression. The aim of this study was to determine th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Fengjun, Schwarz, Brad T., Graham, W. Vallen, Wang, Yingmin, Su, Liping, Clayburgh, Daniel R., Abraham, Clara, Turner, Jerrold R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693969/
https://ncbi.nlm.nih.gov/pubmed/17030185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2006.08.022
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados