TNFα Augments Cytokine-Induced NK Cell IFNγ Production through TNFR2

NK cells play a central role in innate immunity, acting directly through cell-mediated cytotoxicity and by secreting cytokines. TNFα activation of TNFR2 enhances NK cell cytotoxicity, but its effects on the other essential function of NK cells - cytokine production, for which IFNγ is paramount - are...

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Bibliographic Details
Published in:J Innate Immun
Main Authors: Almishri, Wagdi, Santodomingo-Garzon, Tania, Le, Tyson, Stack, Danuta, Mody, Christopher H., Swain, Mark G.
Format: Artigo
Language:Inglês
Published: S. Karger AG 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738838/
https://ncbi.nlm.nih.gov/pubmed/27560480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448077
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