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Wilms Tumor Suppressor, WT1, Suppresses Epigenetic Silencing of the β-Catenin Gene
The mammalian kidney is derived from progenitor cells in intermediate mesoderm. During embryogenesis, progenitor cells expressing the Wilms tumor suppressor gene, WT1, are induced to differentiate in response to WNT signals from the ureteric bud. In hereditary Wilms tumors, clonal loss of WT1 preclu...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303678/ https://ncbi.nlm.nih.gov/pubmed/25331950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.573576 |
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