Wilms Tumor Suppressor, WT1, Cooperates with MicroRNA-26a and MicroRNA-101 to Suppress Translation of the Polycomb Protein, EZH2, in Mesenchymal Stem Cells

Hereditary forms of Wilms arise from developmentally arrested clones of renal progenitor cells with biallelic mutations of WT1; recently, it has been found that Wilms tumors may also be associated with biallelic mutations in DICER1 or DROSHA, crucial for miRNA biogenesis. We have previously shown th...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Akpa, Murielle M., Iglesias, Diana, Chu, LeeLee, Thiébaut, Antonin, Jentoft, Ida, Hammond, Leah, Torban, Elena, Goodyer, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759161/
https://ncbi.nlm.nih.gov/pubmed/26655220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678029
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