Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth

The cyclin D1 gene encodes the regulatory subunit of a holoenzyme that drives cell autonomous cell cycle progression and proliferation. Herein we show cyclin D1 abundance is increased >30-fold in the stromal fibroblasts of patients with invasive breast cancer, associated with poor outcome. Cyclin...

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書誌詳細
出版年:Oncotarget
主要な著者: Pestell, Timothy G., Jiao, Xuanmao, Kumar, Mukesh, Peck, Amy R., Prisco, Marco, Deng, Shengqiong, Li, Zhiping, Ertel, Adam, Casimiro, Mathew C., Ju, Xiaoming, Di Rocco, Agnese, Di Sante, Gabriele, Katiyar, Sanjay, Shupp, Alison, Lisanti, Michael P., Jain, Pooja, Wu, Kongming, Rui, Hallgeir, Hooper, Douglas C., Yu, Zuoren, Goldman, Aaron R., Speicher, David W., Laury-Kleintop, Lisa, Pestell, Richard G.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
Priority Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669846/
https://ncbi.nlm.nih.gov/pubmed/29137220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19953
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