Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis

Cyclin D1 is an important molecular driver of human breast cancer but better understanding of its oncogenic mechanisms is needed, especially to enhance efforts in targeted therapeutics. Currently, pharmaceutical initiatives to inhibit cyclin D1 are focused on the catalytic component since the transf...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Casimiro, Mathew C., Di Sante, Gabriele, Crosariol, Marco, Loro, Emanuele, Dampier, William, Ertel, Adam, Yu, Zuoren, Saria, Elizabeth A., Papanikolaou, Alexandros, Li, Zhiping, Wang, Chenguang, Addya, Sankar, Lisanti, Michael P., Fortina, Paolo, Cardiff, Robert D., Tozeren, Aydin, Knudsen, Erik S., Arnold, Andrew, Pestell, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496164/
https://ncbi.nlm.nih.gov/pubmed/25940700
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