Cyclin D1 Induction of Dicer Governs MicroRNA Processing and Expression in Breast Cancer

Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates the pRB protein and promotes G(1)/S cell cycle progression and oncogenesis. Dicer is a central regulator of miRNA maturation, encoding an enzyme that cleaves double strand RNA or stem-loop-stem RNA into 20–25 nucleotide lon...

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Autori principali: Yu, Zuoren, Wang, Liping, Wang, Chenguang, Ju, Xiaoming, Wang, Min, Chen, Ke, Loro, Emanuele, Li, Zhiping, Zhang, Yuzhen, Wu, Kongming, Casimiro, Mathew C., Gormley, Michael, Ertel, Adam, Fortina, Paolo, Chen, Yihan, Tozeren, Aydin, Liu, Zhongmin, Pestell, Richard G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874416/
https://ncbi.nlm.nih.gov/pubmed/24287487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3812
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