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Cyclin D1 Induction of Dicer Governs MicroRNA Processing and Expression in Breast Cancer
Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates the pRB protein and promotes G(1)/S cell cycle progression and oncogenesis. Dicer is a central regulator of miRNA maturation, encoding an enzyme that cleaves double strand RNA or stem-loop-stem RNA into 20–25 nucleotide lon...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874416/ https://ncbi.nlm.nih.gov/pubmed/24287487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3812 |
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