Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis

Cyclin D1 is an important molecular driver of human breast cancer but better understanding of its oncogenic mechanisms is needed, especially to enhance efforts in targeted therapeutics. Currently, pharmaceutical initiatives to inhibit cyclin D1 are focused on the catalytic component since the transf...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Casimiro, Mathew C., Di Sante, Gabriele, Crosariol, Marco, Loro, Emanuele, Dampier, William, Ertel, Adam, Yu, Zuoren, Saria, Elizabeth A., Papanikolaou, Alexandros, Li, Zhiping, Wang, Chenguang, Addya, Sankar, Lisanti, Michael P., Fortina, Paolo, Cardiff, Robert D., Tozeren, Aydin, Knudsen, Erik S., Arnold, Andrew, Pestell, Richard G.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Priority Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496164/
https://ncbi.nlm.nih.gov/pubmed/25940700
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