microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling

microRNAs are thought to regulate tumor progression and invasion via direct interaction with target genes within cells. Here the microRNA17/20 cluster is shown to govern cellular migration and invasion of nearby cells via heterotypic secreted signals. microRNA17/20 abundance is reduced in highly inv...

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Main Authors: Yu, Zuoren, Willmarth, Nicole E., Zhou, Jie, Katiyar, Sanjay, Wang, Min, Liu, Yang, McCue, Peter A., Quong, Andrew A., Lisanti, Michael P., Pestell, Richard G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889540/
https://ncbi.nlm.nih.gov/pubmed/20406904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002080107
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