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Somatic Excision Demonstrates that c-Jun Induces Cellular Migration and Invasion through Induction of Stem Cell Factor

Cancer cells arise through sequential acquisition of mutations in tumor suppressors and oncogenes. c-Jun, a critical component of the AP-1 complex, is frequently overexpressed in diverse tumor types and has been implicated in promoting cellular proliferation, migration, and angiogenesis. Functional...

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Detalhes bibliográficos
Main Authors: Katiyar, Sanjay, Jiao, Xuanmao, Wagner, Erwin, Lisanti, Michael P., Pestell, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800718/
https://ncbi.nlm.nih.gov/pubmed/17145782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01061-06
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