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c-Jun Induces Mammary Epithelial Cellular Invasion and Breast Cancer Stem Cell Expansion

The molecular mechanisms governing breast tumor cellular self-renewal contribute to breast cancer progression and therapeutic resistance. The ErbB2 oncogene is overexpressed in ∼30% of human breast cancers. c-Jun, the first cellular proto-oncogene, is overexpressed in human breast cancer. However, t...

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Главные авторы: Jiao, Xuanmao, Katiyar, Sanjay, Willmarth, Nicole E., Liu, Manran, Ma, Xiaojing, Flomenberg, Neal, Lisanti, Michael P., Pestell, Richard G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832973/
https://ncbi.nlm.nih.gov/pubmed/20053993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.100792
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