The canonical NF-κB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion

The role of mammary tumor epithelial cell (MEC) NF-κB in tumor progression in vivo is unknown as murine NF-κB components and kinases are either required for murine survival or interfere with normal mammary gland development. As NF-κB inhibitors block both tumor-associated macrophages (TAM) and MEC N...

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Autors principals: Liu, Manran, Sakamaki, Toshiyuki, Casimiro, Mathew C., Willmarth, Nicole, Quong, Andrew A., Ju, Xiaoming, Ojeifo, John, Jiao, Xuanmao, Yeow, Wen-Shuz, Katiyar, Sanjay, Shirley, L. Andrew, Joyce, David, Lisanti, Michael P., Albanese, Christopher, Pestell, Richard G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010731/
https://ncbi.nlm.nih.gov/pubmed/21159656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0732
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