Nuclear Factor-κB Enhances ErbB2-Induced Mammary Tumorigenesis and Neoangiogenesis in Vivo

The (HER2/Neu) ErbB2 oncogene is commonly overexpressed in human breast cancer and is sufficient for mammary tumorigenesis in transgenic mice. Nuclear factor (NF)-κB activity is increased in both human and murine breast tumors. The immune response to mammary tumorigenesis may regulate tumor progress...

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Detalhes bibliográficos
Main Authors: Liu, Manran, Ju, Xiaoming, Willmarth, Nicole E., Casimiro, Mathew C., Ojeifo, John, Sakamaki, Toshiyuki, Katiyar, Sanjay, Jiao, Xuanmao, Popov, Vladimir M., Yu, Zuoren, Wu, Kongming, Joyce, David, Wang, Chenguang, Pestell, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671278/
https://ncbi.nlm.nih.gov/pubmed/19349372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080706
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