ErbB2 Induces Notch1 Activity and Function in Breast Cancer Cells

The ErbB2 (Her2/neu epidermal growth receptor family) oncogene is overexpressed in 30% to 40% of human breast cancers. Cyclin D1 is the regulatory subunit of the holoenzyme that phosphorylates and inactivates the retinoblastoma (pRb) tumor suppressor and is an essential downstream target of ErbB2‐in...

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Detalhes bibliográficos
Main Authors: Lindsay, Jaime, Jiao, Xuanmao, Sakamaki, Toshiyuki, Casimiro, Mathew C., Shirley, Lawrence A., Tran, Thai H., Ju, Xiaoming, Liu, Manran, Li, Zhiping, Wang, Chenguang, Katiyar, Sanjay, Rao, Mahadev, Allen, Kathleen G., Glazer, Robert I., Ge, Changhui, Stanley, Pamela, Lisanti, Michael P., Rui, Hallgeir, Pestell, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590841/
https://ncbi.nlm.nih.gov/pubmed/20443831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00041.x
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