ErbB2 Induces Notch1 Activity and Function in Breast Cancer Cells

The ErbB2 (Her2/neu epidermal growth receptor family) oncogene is overexpressed in 30% to 40% of human breast cancers. Cyclin D1 is the regulatory subunit of the holoenzyme that phosphorylates and inactivates the retinoblastoma (pRb) tumor suppressor and is an essential downstream target of ErbB2‐in...

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Détails bibliographiques
Auteurs principaux: Lindsay, Jaime, Jiao, Xuanmao, Sakamaki, Toshiyuki, Casimiro, Mathew C., Shirley, Lawrence A., Tran, Thai H., Ju, Xiaoming, Liu, Manran, Li, Zhiping, Wang, Chenguang, Katiyar, Sanjay, Rao, Mahadev, Allen, Kathleen G., Glazer, Robert I., Ge, Changhui, Stanley, Pamela, Lisanti, Michael P., Rui, Hallgeir, Pestell, Richard G.
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Inc 2008
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590841/
https://ncbi.nlm.nih.gov/pubmed/20443831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00041.x
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