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Cyclin D1 Determines Mitochondrial Function In Vivo
The cyclin D1 gene encodes a regulatory subunit of the holoenzyme that phosphorylates and inactivates the pRb tumor suppressor to promote nuclear DNA synthesis. cyclin D1 is overexpressed in human breast cancers and is sufficient for the development of murine mammary tumors. Herein, cyclin D1 is sho...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592725/ https://ncbi.nlm.nih.gov/pubmed/16809779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02074-05 |
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