Cyclin D1 Determines Mitochondrial Function In Vivo

The cyclin D1 gene encodes a regulatory subunit of the holoenzyme that phosphorylates and inactivates the pRb tumor suppressor to promote nuclear DNA synthesis. cyclin D1 is overexpressed in human breast cancers and is sufficient for the development of murine mammary tumors. Herein, cyclin D1 is sho...

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Bibliographic Details
Main Authors: Sakamaki, Toshiyuki, Casimiro, Mathew C., Ju, Xiaoming, Quong, Andrew A., Katiyar, Sanjay, Liu, Manran, Jiao, Xuanmao, Li, Anping, Zhang, Xueping, Lu, Yinan, Wang, Chenguang, Byers, Stephen, Nicholson, Robert, Link, Todd, Shemluck, Melvin, Yang, Jianguo, Fricke, Stanley T., Novikoff, Phyllis M., Papanikolaou, Alexandros, Arnold, Andrew, Albanese, Christopher, Pestell, Richard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592725/
https://ncbi.nlm.nih.gov/pubmed/16809779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02074-05
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