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Cyclin D1 Determines Mitochondrial Function In Vivo
The cyclin D1 gene encodes a regulatory subunit of the holoenzyme that phosphorylates and inactivates the pRb tumor suppressor to promote nuclear DNA synthesis. cyclin D1 is overexpressed in human breast cancers and is sufficient for the development of murine mammary tumors. Herein, cyclin D1 is sho...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2006
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592725/ https://ncbi.nlm.nih.gov/pubmed/16809779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02074-05 |
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