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C-jun Inhibits Mammary Apoptosis In Vivo

c-jun, which is overexpressed in a number of human cancers encodes a critical component of the AP-1 complex. c-jun has been shown to either induce or inhibit cellular apoptosis. Germ line deletion of both c-jun alleles is embryonically lethal. To determine the role of the endogenous c-jun gene in ap...

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Detalhes bibliográficos
Main Authors: Katiyar, Sanjay, Casimiro, Mathew C., Dettin, Luis, Ju, Xiaoming, Wagner, Erwin F., Tanaka, Hirokazu, Pestell, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993753/
https://ncbi.nlm.nih.gov/pubmed/20926681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-08-0705
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