microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling

microRNAs are thought to regulate tumor progression and invasion via direct interaction with target genes within cells. Here the microRNA17/20 cluster is shown to govern cellular migration and invasion of nearby cells via heterotypic secreted signals. microRNA17/20 abundance is reduced in highly inv...

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Autores principales: Yu, Zuoren, Willmarth, Nicole E., Zhou, Jie, Katiyar, Sanjay, Wang, Min, Liu, Yang, McCue, Peter A., Quong, Andrew A., Lisanti, Michael P., Pestell, Richard G.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889540/
https://ncbi.nlm.nih.gov/pubmed/20406904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002080107
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