Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth

The cyclin D1 gene encodes the regulatory subunit of a holoenzyme that drives cell autonomous cell cycle progression and proliferation. Herein we show cyclin D1 abundance is increased >30-fold in the stromal fibroblasts of patients with invasive breast cancer, associated with poor outcome. Cyclin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Pestell, Timothy G., Jiao, Xuanmao, Kumar, Mukesh, Peck, Amy R., Prisco, Marco, Deng, Shengqiong, Li, Zhiping, Ertel, Adam, Casimiro, Mathew C., Ju, Xiaoming, Di Rocco, Agnese, Di Sante, Gabriele, Katiyar, Sanjay, Shupp, Alison, Lisanti, Michael P., Jain, Pooja, Wu, Kongming, Rui, Hallgeir, Hooper, Douglas C., Yu, Zuoren, Goldman, Aaron R., Speicher, David W., Laury-Kleintop, Lisa, Pestell, Richard G.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Priority Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669846/
https://ncbi.nlm.nih.gov/pubmed/29137220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19953
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker