Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth

The cyclin D1 gene encodes the regulatory subunit of a holoenzyme that drives cell autonomous cell cycle progression and proliferation. Herein we show cyclin D1 abundance is increased >30-fold in the stromal fibroblasts of patients with invasive breast cancer, associated with poor outcome. Cyclin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncotarget
मुख्य लेखकों: Pestell, Timothy G., Jiao, Xuanmao, Kumar, Mukesh, Peck, Amy R., Prisco, Marco, Deng, Shengqiong, Li, Zhiping, Ertel, Adam, Casimiro, Mathew C., Ju, Xiaoming, Di Rocco, Agnese, Di Sante, Gabriele, Katiyar, Sanjay, Shupp, Alison, Lisanti, Michael P., Jain, Pooja, Wu, Kongming, Rui, Hallgeir, Hooper, Douglas C., Yu, Zuoren, Goldman, Aaron R., Speicher, David W., Laury-Kleintop, Lisa, Pestell, Richard G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2017
विषय:
Priority Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669846/
https://ncbi.nlm.nih.gov/pubmed/29137220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19953
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