Synthetic regulatory RNAs selectively suppress the progression of bladder cancer

The traditional treatment for cancer is lack of specificity and efficacy. Modular synthetic regulatory RNAs, such as inhibitive RNA (iRNA) and active RNA (aRNA), may overcome these limitations. Here, we synthesize a new iRNA to bind the upstream activating sequence (UAS) of a minimal promoter that d...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zhuang, Chengle, Huang, Xinbo, Zhuang, Changshui, Luo, Xiaomin, Zhang, Xiaowei, Cai, Zhiming, Gui, Yaoting
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663129/
https://ncbi.nlm.nih.gov/pubmed/29084575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0626-x
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