A CRISPR Interference of CBP and p300 Selectively Induced Synthetic Lethality in Bladder Cancer Cells In Vitro

The transcriptional coactivator CREB-binding protein (CBP) and p300 are adenoviral E1A-binding proteins involved in various cellular processes, including embryonic development, homeostasis, cell differentiation and transcription activation. Previous study suggested that synthetic lethality between C...

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Publicat a:Int J Biol Sci
Autors principals: Li, Jianfa, Huang, ChenChen, Xiong, Tiefu, Zhuang, Changshui, Zhuang, Chengle, Li, Yawen, Ye, Jing, Gui, Yaoting
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567804/
https://ncbi.nlm.nih.gov/pubmed/31223286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.32332
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