Engineered CRISPR/Cas13d Sensing hTERT Selectively Inhibits the Progression of Bladder Cancer In Vitro

Aptazyme and CRISPR/Cas gene editing system were widely used for regulating gene expression in various diseases, including cancer. This work aimed to reconstruct CRISPR/Cas13d tool for sensing hTERT exclusively based on the new device OFF-switch hTERT aptazyme that was inserted into the 3’ UTR of th...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Front Mol Biosci
Главные авторы: Zhuang, Chengle, Zhuang, Changshui, Zhou, Qun, Huang, Xueting, Gui, Yaoting, Lai, Yongqing, Yang, Shangqi
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Molecular Biosciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017217/
https://ncbi.nlm.nih.gov/pubmed/33816560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.646412
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы