N6‐methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO‐PGC‐1α signalling axis

The abundant and reversible N6‐methyladenosine (m6A) RNA modification and its modulators have important roles in regulating various gene expression and biological processes. Here, we demonstrate that fat mass and obesity associated (FTO), as an m6A demethylase, plays a critical anti‐tumorigenic role...

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Bibliografische gegevens
Gepubliceerd in:J Cell Mol Med
Hoofdauteurs: Zhuang, Changshui, Zhuang, Chengle, Luo, Xiaomin, Huang, Xinbo, Yao, Lv, Li, Jianfa, Li, Yawen, Xiong, Tiefu, Ye, Jing, Zhang, Fangting, Gui, Yaoting
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378205/
https://ncbi.nlm.nih.gov/pubmed/30648791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14128
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