N6‐methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO‐PGC‐1α signalling axis

The abundant and reversible N6‐methyladenosine (m6A) RNA modification and its modulators have important roles in regulating various gene expression and biological processes. Here, we demonstrate that fat mass and obesity associated (FTO), as an m6A demethylase, plays a critical anti‐tumorigenic role...

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發表在:J Cell Mol Med
Main Authors: Zhuang, Changshui, Zhuang, Chengle, Luo, Xiaomin, Huang, Xinbo, Yao, Lv, Li, Jianfa, Li, Yawen, Xiong, Tiefu, Ye, Jing, Zhang, Fangting, Gui, Yaoting
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378205/
https://ncbi.nlm.nih.gov/pubmed/30648791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14128
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